Decipher Results and Outcomes: Anyone had similar?

Posted by namrac @namrac, Jan 3 7:05pm

I am curious if others have had similar results on their decipher test and outcome. I have added my results and up to date information.

I was diagnosed with a PSA level of 5.5 two years ago. Eight months earlier, it was 2.5. I wasn't feeling well, so I had a complete battery of tests, all of which came back negative. My doctor suggested running a PSA test, which I agreed to, and thus began my journey.

I had a prostatectomy on January 16, 2023. Four lymph nodes and the left seminal vesicles were positive and removed, along with a total of 19 lymph nodes but there was no distant spread Stage 4a. My PSA level was undetectable 8 weeks post-surgery and remained undetectable for the first 6 months. Then it started to rise slowly. When it reached 0.13. Off to the oncologist (who only does pc for 20 plus years) on April 9, 2024, and started Orgovyx.
Before starting radiation therapy, my PSA was undetectable again because of this drug I began radiation on April 23, 2024. After radiation my PSA was >.01 until October 2024 where it went to .02 which freaked me out a bit, not the oncologist.

I had my surgeons appointment in November and my PSA came back >.02 which I think is as low as his lab goes unlike the oncologist. I felt a bit better this time . I would love to head others experiences it helps.

Shared files

Decipher Redacted_Signed (Decipher-Redacted_Signed-3.pdf)

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

@imbimbo

So this tells me that there is little science in these scores unless the slides are so obviously abnormal. I had two biopsies with first being interpreted as 3+4 and then read at Hopkins giving them a 3+3. A second biopsy a year later was 3+3 verified using AI. I get a third biopsy on Monday afternoon. My decipher on the first biopsy came at .37 low risk.

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Why not use PSE or EpiCaPture tests? They would show the presence of aggressive cancer needing treatment.

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@heavyphil

Why not use PSE or EpiCaPture tests? They would show the presence of aggressive cancer needing treatment.

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Never heard of these and doctors never mentioned them.

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@imbimbo

Never heard of these and doctors never mentioned them.

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They are new so probably not mainstream yet. But there are other urine tests you should research.

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