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DiscussionNewly diagnosed CLL How to interpret FISH results?
Blood Cancers & Disorders | Last Active: 13 hours ago | Replies (9)Comment receiving replies
Replies to "I’m 78 recently diagnosed 3 stage MM. Fish test 50%. Went for second opinion, Fish test..."
Keep track of any symptoms (good and not) associated with the MM and DRVD treatment. It is good to ask the doctor which mutation(s) that you have and the potential impact on treatment and remission of MM. Are there foods, drugs, or activities that you should do or avoid, including pain management. Here is a site for questions one can ask: https://www.cancer.org/cancer/types/multiple-myeloma/detection-diagnosis-staging/talking-with-doctor.html
I'm 70 and still at the asymptomatic MGUS stage with 15% plasma cells based on my latest bone marrow biopsy. I have the 1q21 gain mutation; that means that I have one gene duplicated on chromosome 1 on the long arm (q) at location 21 (a geneticists' version of a road map). If it had been amplification rather than gain then the mutated gene would have been 3 times rather than 2 (gain). The mutation puts me at some risk of the MGUS progressing to MM. Not all genetic mutations are bad, some buffer effects of bad mutations. https://www.cancer.gov/news-events/cancer-currents-blog/2024/multiple-myeloma-darzalex-plus-vrd