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@ajand

Hi, I am newly diagnosed with HOCM after physician heard a murmur at routine checkup. Awaiting cardiology appt this week. I have sigmoid ventricular septum that is causing the obstruction. I have been treated for hypertension for 5-6 years although always had hypertension with each of my pregnancies. I have had continuous weight gain over last 3 years of about 7-8 lbs per year. I thought the pressure in my chest and sob was just related to being fat and out of shape when on walks or even just walking up a flight of stairs. Prior to this my weight had always remained pretty steady-i am 47 years old and contributed wt gain to metabolism slowing down as menopause approached. Since this spring I have had chronic cough after respiratory infection that I couldn’t get rid of. Also have had dizziness on standing and with bending over and straightening again for some time, recently getting worse. Since my echo I have had increasing chest pain with going for walks- some days being better than others. Also have been having a lot of palpitations and occassional heart arrythmias noted. Currently on losartan/hctz 100mg-12.5 mg for blood pressure . Have backed off of lasix with new diagnosis as contraindicated per pcp recommendation. I am yet to have a stress echo. Also have been experiencing a head rush type of feeling in my head lately. I am a RN so understand alot of this- but question when there is obstruction how likely are medications supposed to work and is that just going to be a temporary bandaid until surgery is needed? Thanks in advance. I think this is a great site for people to get information and am very grateful to all those who contribute. Also doctor through Mayo in Eau Claire/ Menomonie Wi and live 90 minutes from Rochester so am fortunate that way.

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Replies to "Hi, I am newly diagnosed with HOCM after physician heard a murmur at routine checkup. Awaiting..."

Welcome to Connect, @ajand.
I’m tagging @archer @rrowner2 @falconfly as they’ve shared their experiences about medications in this discussion:
– MEDS FOR HCM - DOSAGE https://connect.mayoclinic.org/discussion/meds-for-hcm-dosage/

I also thought you might be interested in reading about a new drug trial which has shown promising results for HCM/HOCM patients:
– Mavacamten Treatment for Obstructive Hypertrophic Cardiomyopathy: A Clinical Trial.
https://www.biospace.com/article/clinical-trial-results-from-myokardia-s-phase-2-pioneer-hcm-study-of-mavacamten-published-in-the-annals-of-internal-medicine/

Connect’s Alumna Mentor, @cynaburst had mentioned that, "Losartan is not a medication that is commonly used in HCM.” May I ask if you are seeing an HCM specialist?

ajand ...all you described could have been me. I'm surprised your Dr diagnosed you with HOCM. A murmur alone doesn't tell them that. It wasn't until my cardiologist did an echo (among other tests) and found the the thickened heart muscle that he said I had HOCM. We tried medicines that didn't really help so the end of Aug I had a Septal Myectomy. Two different doctors here told me not to have the surgery anywhere except the Mayo in Rochester Mn which is where I had it. Tests had to be repeated there even tho they had everything from here...just making sure of everything I guess. I could never live in Mn because of your weather but I think people there are so blessed to have Mayo at their fingertips.

My husband had an SM last October at Rochester, 6 months prior to surgery he was on max ( toxic) amounts of meds and they had stopped fully managing his symptoms the side effects were increasing. Apart from all this he was in good physical shape, no diabetes etc. soooo the surgery was amazing he recovered quickly and was back to “normal” still has cardiomyopathy but no obstruction. He/we were beyond impressed with everything about our experience at Mayo.