Transdermal HRT

Posted by vkmov @vkmov, Oct 19, 2023

Many studies have found that transdermal HRT protects and builds bone without all the horrific side effects of many first-line osteoporosis treatments. The patch bypasses the liver and thereby avoids the risks of breast cancer, strokes, etc. Has anyone explored this or discussed it with their doctors?

Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.

@mayblin

It appears no studies had been done as to how well transdermal HRT will hold the bmd gains from anabolics (forteo, tymlos or evenity). I've read from studies that the rate of bmd loss after stopping Forteo without any intervention is a lot higher than that in a typical case of osteoporosis due to estrogen-difficiency. A plan B should be in place should relying on HRT alone turn out to be not sufficient enough. Id think op due to secondary cause(s) most likely requires additional intervention.

Many thanks to @teb for paving the way and sharing personal experiences.

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Thank you for those kind words. Happy to share as we're all in this darn big boat together!
I'll be going for a Dexa in a couple of months and am going to try to get a REMS Echolight as well. With my increased HRT dose and increased weight training, it will be interesting to see if there has been any positive impact. That said, this is the first year I've lost significant height which concerns me. I was always surprised that in the many years since menopause, I had only lost 1/2" of height when friends without an osteoporosis diagnosis had easily lost 1-2". My osteoporosis caused scoliosis as of 15-20 years ago so perhaps that is finally catching up with me. I have a protocol of Scroth stretches that I am supposed to do daily but it often falls by the wayside between core exercises, walking, dancing and lifting weights.
New Year's resolution! I've got to get back to doing it daily as I think it is very helpful and I'd highly recommend to all whether you have scoliosis or not. Even just a basic hanging stretch is helpful. Really great for elongating the spine, putting a little breathing room between those vertebrae!

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Hello,
I will be consulting with a hematologist this month because I have factor five leiden heterozygous which puts me more at risk for blood clots. I have taken oral birth control pills in my 20s, 30s and mostly in my 40's without any problem. Hopefully she will agree with me taking transdermal bioidentical hrt. I'm sure she'll do some labwork too. Transdermal hrt by passes the liver and doesn't put a person at risk for breast cancer or blood clots. But try and convince a doctor remains a question in my mind. 🤞

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I've never taken any drugs for bone loss, but have gotten improvement in my DEXA scan when I started a transdermal estradiol patch. Creams did not work.

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@wildapple50

I've never taken any drugs for bone loss, but have gotten improvement in my DEXA scan when I started a transdermal estradiol patch. Creams did not work.

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Can you share your numbers on the Dexa and how long you used the estrogen patch to see improvements? I am on estradiol patch .075 2x/week. I just started.

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@wildapple50

I've never taken any drugs for bone loss, but have gotten improvement in my DEXA scan when I started a transdermal estradiol patch. Creams did not work.

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I would be interested as well. I am trying to figure out what dose of the patch and testosterone pellet may have the biggest impact on my bones. Started on .025 and now .0375. I believe that my provider will be increasing it today. Did you pay out of pocket for additional dexa scan to monitor the impact?

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@teb

Thank you for those kind words. Happy to share as we're all in this darn big boat together!
I'll be going for a Dexa in a couple of months and am going to try to get a REMS Echolight as well. With my increased HRT dose and increased weight training, it will be interesting to see if there has been any positive impact. That said, this is the first year I've lost significant height which concerns me. I was always surprised that in the many years since menopause, I had only lost 1/2" of height when friends without an osteoporosis diagnosis had easily lost 1-2". My osteoporosis caused scoliosis as of 15-20 years ago so perhaps that is finally catching up with me. I have a protocol of Scroth stretches that I am supposed to do daily but it often falls by the wayside between core exercises, walking, dancing and lifting weights.
New Year's resolution! I've got to get back to doing it daily as I think it is very helpful and I'd highly recommend to all whether you have scoliosis or not. Even just a basic hanging stretch is helpful. Really great for elongating the spine, putting a little breathing room between those vertebrae!

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Please keep us posted, thank you.

All the best!

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@mayblin

Please keep us posted, thank you.

All the best!

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Thanks! Will do!

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@gravity3

I would be interested as well. I am trying to figure out what dose of the patch and testosterone pellet may have the biggest impact on my bones. Started on .025 and now .0375. I believe that my provider will be increasing it today. Did you pay out of pocket for additional dexa scan to monitor the impact?

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No, did not pay out of pocket because the scans were 2-3 years apart. The lowest dose that will be effective is 0.05 per a doctor I saw. I do not take testosterone.

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@wildapple50

No, did not pay out of pocket because the scans were 2-3 years apart. The lowest dose that will be effective is 0.05 per a doctor I saw. I do not take testosterone.

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Hi @wildapple50 it is very encouraging to hear your experiences. What is your bmd% increase during the 2-3 years of using HRT if you don't mind sharing? If possible, could you share what age group you are in, or how many years post-menopause you've been? Thanks a lot!

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I don't remember the % of increase but my dr was happy and said there was nothing further to do. I went through menopause at 42. I'm 74 now. I started out using hrt pills, but quit when the WHI scare came out. I didn't do anything for a few years, but then started using hrt creams. These didn't help. When I got on the estradiol patch my dr noticed the improvement. I will continue on with this.

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