Sometimes my eyes burn for a short while after application. That was mentioned when I read about the medication, so I know it is normal. It is tolerable. No other reactions.

Years ago I tried it for dry eyes and it not only burned it made my eyes sore and red. After a few days it was no better and beginning to affect my vision so I quit. Recently my husband had it prescribed for him and he had the same disappointing result and had to quit. I am sure not everyone has this reaction to it. Good luck.