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MGUS and quite high Free Kappa Light Chain and Kappa Lambda Ratio
Blood Cancers & Disorders | Last Active: 5 days ago | Replies (212)Comment receiving replies
All of my inflammatory markers are low
I've been tested by my gastro doc and do not have celiac or food allergies
These findings have chronically been high for over a year. I've been on b12 shots for over a year. My question, more directly is, in the Serum immunoelectrophoresis labels it as iga lambda whereas it's the free kappa is elevated. Can't seem to wrap my head around that and am hoping for an answer
Replies to "All of my inflammatory markers are low I've been tested by my gastro doc and do..."
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Likely need to see an oncologist to get an answer if it was a GP that told you this. Kappa and lambda are on opposite arms (light chains) of a Y shaped antibody. Starting out, my lambda was normal range and kappa was just above, then the kappa started ramping up after a few years, so the kappa/lambda ratio is now ~29. Lambda is still normal. MGUS is a waiting game, seeing how the trends in your bloodwork give up info.