I started Cymbalta three months ago after five different back surgeries in six years left me with all kinds of nerve pain. I had been on Gabapentin for years but it would only help some. Well,it's been a life changer for me. Within two days all of my leftover nerve pain was gone. Yes I had a few side effects but they go away after a couple of weeks for me. My pain and my mood are much better since starting it.