Good morning, @irishgoff82. It’s always so jarring when we get news about our health that we don’t understand, isn’t it? I’ve been there myself and until we learn more about the facts it leaves us rattled and feeling uncertain. I’m so glad that you found Connect. Hopefully I can shed some light on what the mutation in the JAK2 gene could indicate.

The JAK2 gene directs cells to make the JAK2 protein, which stimulates cell growth and division. When there’s a mutation in this gene, it can, for lack of better words, override the control switch to shut off production of certain blood cells which can potentially lead to various health issues. For example, some people may have an over production of red blood cells leading to a diagnosis of PV (polycythemia vera) or a proliferation of platelets in a condition called ET (essential thrombocythemia). The mutation can also cause changes in the bone marrow over time.
However, there are medications which can help control this over production and people live long and healthy lives.

There are quite a few members in Connect who also have the same mutation. We have some lively conversations within the support groups where I think you’ll find you’re not alone We’re all here to share our experiences and to offer hope so that you won’t feel as worried about your recent news.

I’d love to direct you to the right group though so I’ll need a little more information if you don’t mind sharing. You mentioned that your platelets are normal, which is great. Were there other blood test numbers such as hemoglobin or hematocrit that were elevated?
Can you tell me a little more about what led your doctor to order a bone marrow biopsy?