@donnamae90 Fatigue is a problem with MDS. I too live alone. I have accepted that I do not have the stamina or strength that I once had, but I still have a good quality of life. We make changes. This year, I gave up motorcycling after 22 years of riding. I felt that I should not ride when I was tired. Fatigue is still present but not as bad since I am now stabilized on Revlimid. Have you started treatment? Where is your Hemoglobin at?