JAK2+, diagnosed Feb 2024. Counts had been elevated for 3 years, then jumped at annual physical.

Started with 500 and phlebotomies every week. Then 1,000, and phlebotomies every 2 weeks, finally 1,500 and fewer and fewer phlebotomies.

HOWEVER, at first I had a large bruise on my left inner thigh, and I could feel knots a half inch or so under the skin. Then my left ankle began to swell, then the foot too. Finally I started getting a pain in my side, severe enough to it was painful to get in and out of bed, or off the couch and out of a chair.

24 hours after stopping hydroxyurea, pain was nearly gone, and other symptoms have been subsiding. I started 15mg Jakafi 2 times a day a week later.