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Treatment resistant depression help.
I was diagnosed with Interstitial Lung Disease in September 2020, as time went on, I was lucky enough to receive a lung transplant. I have also dealt with chronic back pain for over 25 years. After my experience in hospital, I was left with PTSD and panic attacks. I was seeing a Psychiatrist and taking Mirtazapine, this seemed to have a negative effect on my behaviour and mood so I stopped taking it. In a search for help I tried many avenues only to be met with constant recommendations to take anti-depressants. Eventually I disengaged with the Psychiatrist and began medicinal cannabis. This has to be done carefully as it clashes with Tacrolimus. I have found it to be beneficial but not a magic bullet. Am I alone in having suicidal ideations after having a transplant? I should be grateful for having a second chance, but I am not.
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Thank you for your encouragement.
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1 ReactionI am giving strong consideration to micro-dosing psilocybin. I am yet to research any interactions with the list of medications I am taking. If there is no research, I am willing to just go for it. It is better than ending it all. I have taken psilocybin in the past when I was younger, but that was recreationally and in a large group with a watcher, we took enough to enter another dimension. So, I understand the risks involved if too much is taken. I also believe it has the potential to create a positive mindset if taken responsibly. Unfortunately, it is illegal where I live so I have to wait until they are in season and pick my own. I thank you for the confirmation it has had a positive outcome for you.
I appreciate everyone who has suggested help and will be suggesting those I haven't tried. You prove to me that there are more good people in this world than bad. Despite what I have been through it is people like you that inspire me to keep trying and soldier on, and that is exactly what I will do. Once again thank you to you all.
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3 ReactionsSo true. Pick your poison.
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1 ReactionJust a word of caution when supplementing antidepressants with antipsychotics. I found the combination to be very helpful with my treatment resistant depression. However I now have permanent Tardive Dyskinesia (weird uncontrolled mouth movements) from using Seroquel and Cymbalta with Wellbutrin. I’m 64 and have struggled with chronic severe migraines which exacerbated my depression and have tried just about everything to help with both conditions. I didn’t even know I had the weird mouth movements until I saw myself on a Zoom recording. I was horrified and immediately got off the antipsychotic but the TD never went away. I’m devastated over this permanent side effect. Be careful.
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2 Reactions@mcgrathcreative2
I am sorry to hear of your TD. I have read about this side effect. Which antipsychotic were you on and at what dose? I am on aripiprazole 2 mg and noticed worsening symptoms at 5 mg so they reduced back to 2 mg. Did you have any signs or symptoms before developing permanent TD?
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1 ReactionI don’t remember my dosages, but I had pretty noticeable shakes or tremor from Abilify. People asked me if I had Parkinson’s disease because it was so obvious. I got off the Abilify even though it helped my depression and sleep significantly. So then I was put on Remeron which severely increased my headaches (I’m a long time chronic migraine patient). So I got off of that and I was put on Seroquel. I loved Seroquel because it helped me sleep. It was Seroquel that caused the TD. And like I said, I really wanted to stay on the Seroquel but I didn’t realize I even had TD until I saw myself on a Zoom recording. I was mortified and shocked that no one ever said anything about it to me. What a nightmare. I’m still struggling with sleep. Working with my psychiatrist and sleep specialist. Best of luck to you. Be careful of those antipsychotic meds.
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3 ReactionsI was also put on Seroquel as well as Mirtazapine at the same time. I find myself outspoken with no filter and too willing to engage in a physical altercation. My go to for relief is to think about suicide. I am currently only taking diazepam and medicinal cannabis alongside my regular medication for anti-rejection. Everything I have tried to do to address it is a waste of time, I have been down so many roads that all ended up dead ends it is adding to my depression. I could only imagine how you feel developing such a side effect. It makes you feel like a lab test sometimes the way they just try this and that and then these two. Where I am in Australia, we have Voluntary Assisted Dying I tick six out of seven boxes. I have to be diagnosed with seven months to live, this means I can refuse to take anti-rejection medication and qualify in a short time. This is my happy thought as it empowers me in a weird kind of way.
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1 ReactionI was put on quetiapine and mirtazapine, my theory is what goes up must come down. They may seem to help in the short term which I believe is all because you are taking them and expecting an outcome. But unless you are willing to take them forever the reason you started taking them eventually returns and you are back to square one.
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2 ReactionsOh, I feel your pain. I suffer from severe chronic migraines as well as treatment resistant depression. Yes, I consider myself to be a pharmaceutical guinea pig. 44 years of it. Suicide sounds wonderful. Good luck to you.
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