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← Return to Prolia discontinuation
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@czauderer, the safest transition is Reclast--a bisphsponate. You were only on Prolia for a year, still you have the risk of rebound. I don't blame you for not wanting to transition to a bisphosphonate, but avoiding it could be a worse outcome. And there is a good chance that Reclast wouldn't even be bad.
So what happens you may already know is that while on Prolia the cells that breakdown the bones are held back in the last stages of development. When you stop Prolia all those acid producing cells are released upon your bones. Cascade fractures can result where the vertebra break compress one after the other. Fractured vertebra never heal in the prefracture configuration. You lose height and your spine bends forward. The new configuration is painful even after you heal and leads to other pain as the space where the nerves exit the spine becomes more and more narrow.
Maybe, consider the single injection of Reclast.
Whatever you decide, may you never fracture.
Replies to "@czauderer, the safest transition is Reclast--a bisphsponate. You were only on Prolia for a year, still..."
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Hi I've posted a few times about my dilemma with trying to transition from Prolia to something else due to complications with dental work and possibility of ONJ, but I've never really read the breakdown of what happens during rebound when you go off of Prolia. This is pretty scary given the fact that I have been on Prolia for 6 years, meaning I've had at least 12 injections if not 13. I am due for a Prolia shot end of December early January but I'm waiting to get into the endocrinologist to evaluate my parathyroid activity, which is elevated, and to see what my options are for weaning off Prolia. This doesn't sound to promising to me. Does anyone on the thread know just how long someone can be on Prolia before there are other long-term effects? I'm only 70 years old. What if I stay on Prolia till I croak? That could be another 15 years and 30 more shots?? Why was this medication even put on the market? Certainly wasn't told that people who have extensive dental work should not go on it, not by my doctor... I found out on my own.