I got my MGUS diagnosis in 2010, as I remember, now 86. I have some fatigue, but otherwise not symptomatic. I believe both my husband and I got COVID from our son in January of 2021, after he flew down from New York City to spend five days with us and on the last day was incredibly ill - and of course flew home ill, though wearing a mask and was told he had the flu, though his symptoms were more Covid. When I got tested for antibodies, I was way off the charts positive, which no one could explain to me. I got timely vaccines and think I have not had it again, though a couple of times since I've been very very ill for just a few days, like three, so ill that I could not figure out how the home tests worked and no one was around to help. My most recent vaccine, two weeks ago, was the Novavax, not the spike vaccines. So far so good. I seem to have escaped the immunity issue with MGUS. I have used the Enovid anti-viral nasal spray (I order it from Israel) every time I leave the house or have company, mainly because I can't stand to just do nothing to change the odds. My husband sometimes does as well. No flu, no colds and probably no further Covid.