Gleason 6 But high decipher score.

I am a bit loss on the numericals for decipher score.....what is the range? I know someone who has a .44 decipher score. Is this high risk, medium? Low? So far 3 and 3 gleason but new stuff shown up and new biopsy in near future. thank you.

Thanks a ton @retireditguy and @robertmizek, good info both of you. I was wracking my brain earlier wondering why I had ruled out Brachytherapy and i just remembered: somewhere I read that the seeds will make me radioactive toward others and close contact is not recommended for a short time. My mind went immediately to my new (1st) grandson, and my daughter’s paranoia about him getting sick. If she were to hear that I might be radioactive she’d probably ask me not to hold or play with him. That would break my heart! Have either of you heard that about Brachy?

I am a bit loss on the numericals for decipher score.....what is the range? I know someone who has a .44 decipher score. Is this high risk, medium? Low? So far 3 and 3 gleason but new stuff shown up and new biopsy in near future. thank you.

Hey caryg1955 and others - Sounds like I am in a similar place as you and others. After having a partial nephrectomy in July at Cleveland Clinic in Ohio, I had an mpMRI after having a slow but consistent rise in my PSA from 1 to 5 over seven years. With the MRI revealing a .6 cm PI-RADS 4 lesion, I then had a transperineal fusion biopsy revealing four of nine positive cores (two at 5%, one at 15% and one at 35%) and all at Gleason score 3 = 3 =6 Grade Group 1. I then opted for the Decipher test given family history of aggressive prostate cancer and got the results a few days ago showing a high risk at .78. Will be circling back with my surgical oncologist although I suspect he will recommend surgery given the high Decipher score. Although I have great confidence in my surgeon, I will at least consider consulting with a radiation oncologist for a second opinion and will push for PSMA and bone scans to rule out spreading.
Would greatly appreciate hearing about the decision you made and from others who might have thoughts or comments.
All the best to you.

Decipher range is from 0 to 1 so .44 would be in the medium range risk.
I have a relatively low but continuing to rise PSA currently at 5 and a Gleason Score of 3+3=6 for all four of nine cores of the biopsy. So was leaning towards active surveillance until a .78 Decipher score came back earlier this week. Awaiting my next appointment to consider appropriate treatment.

Hi hirejohn my situation is very similar to yours. I’m 67 years old and have been on active surveillance for 5 years. All previous biopsies had been 3+3=6 in 3-5 out of 14 samples usually around 10%. My last biopsies came back as 3+4=7 in 5 samples. So I sent my slides to John Hopkins for a second opinion. By the way it is a very easy process and my out of pocket was some where around $ 200.00. John Hopkins said all samples were 3+3=6. So that lead me to getting the decipher test which came back in the high range. And that’s what drives me crazy about this whole process. After weighing all my options I went with 28 sessions of IMRT which I finished on October 24 2024. I know we all can have different experiences but for me the bladder prep was the most challenging. I also changed my diet to high protein low gassy foods and kept up my exercising walking 5-6 miles daily. My side effects were pretty mild and by 2 weeks after treatment things were much better. Some people have strong opinions on what direction to take I don’t. This is a very personal battle and you are doing the right thing by asking questions and checking on others experiences. I wish you the very best. Hang in there.

Hi hirejohn my situation is very similar to yours. I’m 67 years old and have been on active surveillance for 5 years. All previous biopsies had been 3+3=6 in 3-5 out of 14 samples usually around 10%. My last biopsies came back as 3+4=7 in 5 samples. So I sent my slides to John Hopkins for a second opinion. By the way it is a very easy process and my out of pocket was some where around $ 200.00. John Hopkins said all samples were 3+3=6. So that lead me to getting the decipher test which came back in the high range. And that’s what drives me crazy about this whole process. After weighing all my options I went with 28 sessions of IMRT which I finished on October 24 2024. I know we all can have different experiences but for me the bladder prep was the most challenging. I also changed my diet to high protein low gassy foods and kept up my exercising walking 5-6 miles daily. My side effects were pretty mild and by 2 weeks after treatment things were much better. Some people have strong opinions on what direction to take I don’t. This is a very personal battle and you are doing the right thing by asking questions and checking on others experiences. I wish you the very best. Hang in there.