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Relapse endometrial cancer

Gynecologic Cancers | Last Active: Dec 11, 2024 | Replies (56)

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@naturegirl5

@idaho1960. I just posted a message to you on another discussion and asked how we can can support you. I also asked about your diagnosis which you have kindly expanded upon here. It sounds like your treatment plans are moving quickly and that's good.

You raise some very good questions. My diagnosis was adenocarcinoma, endometroid type FIGO Grade 1. Same as you. I did have a recurrence that was found in the vaginal cuff. It was two years and a few months after the radical hysterectomy. I had a PET/MR scan after the recurrence was found in the vaginal cuff and those scans showed no evidence of disease.

My surgeon told me after the hysterectomy that I would return every 6 months for physical pelvic exams but no CT scans. She said that the majority of recurrences are found on the vaginal cuff. It was during one of those exams that the recurrence was found on the vaginal cuff. After many discussions (I had external pelvic radiation and 2 treatments of brachytherapy) I figured that maybe something was "missed" in pathology in the cervix. After all, pathology takes a sampling of tissue and cannot examine every single piece of tissue that is removed. Maybe there needs to be a change in protocol where more of the cervix is examined? And what would have happened had I had the radiation therapy after I was healed from the hysterectomy? I was staged 1a after the hysterectomy which means no other treatment was recommended at that time.

So you do raise some really good questions. Would you like to write these questions down and ask your oncology surgeon? And then come back here and let me know what your surgeon says?

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Replies to "@idaho1960. I just posted a message to you on another discussion and asked how we can..."

I’m in same situation recurrence in vaginal cuff 2 yrs after hysterectomy followed with external radiation and 5 intense brachytherapy I thought there couldn’t possibly be anything left but two months ago I had a positive signatera test so now I am on Jemperli immunotherapy drug
But this stubborn thing although microscopic keeps lighting up on PET scan
Pelvic exam totally normal. we are hoping the Jemperli is working but how long can I stay on it? I’ve set up second and third opinion appts