1. < Gynecologic Cancers

Anyone else had letrozole to treat uterine cancer?

Posted by cookercooker @cookercooker, Nov 27 11:24am

I was just put on letrozole after having 6 round of chemo. I don't hold much hope in this treatment as it has a 9% efficacy rating, but my doc said it has one of the least side effects. Have been taking it for 10 days now and have started bleeding--not spotting. Was wondering if anyone else has had the same experience.

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cookercooker | @cookercooker | Dec 5 1:21pm
In reply to @crowleykid "@cookercooker I am in a clinical trial and the two drugs are letrozole and verzenio (abimacyclib)...." + (show)
@crowleykid

@cookercooker
I am in a clinical trial and the two drugs are letrozole and verzenio (abimacyclib). They feel that my tumor was estrogen based so they gave me two breast cancer drugs and the tumor went away for the 2nd time. I did not have any issues with letrozole but the verzenio affected my kidneys (GFR). We now think it might be affecting the prednisone which is trying to get rid of the organizing pneumonia. I have had the pneumonia for 16 months & I believe I it got from the immunotherapy drug keytruda (pembrolizumab).
I hope this information is helpful to you.

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Thank you for the heads-up. I'm only on Letrozole at the moment,, and expect that I will need something else in the very near future. This is because Letrozole has only a 9% efficacy rate. If verzenio is suggested, I'll let the oncologist know about the fx you are experiencing with it.

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cookercooker | @cookercooker | Dec 5 1:23pm
In reply to @colleenyoung "@cookercooker, I'm tagging fellow members like @slanepac2024 @doshi @tbkomparda @crowleykid @cjacobs99 who have experience with letrozole..." + (show)
@colleenyoung

@cookercooker, I'm tagging fellow members like @slanepac2024 @doshi @tbkomparda @crowleykid @cjacobs99 who have experience with letrozole (Femara) for endometrial cancer.

Cooker, how are you doing? Has the bleeding stopped?

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Thanks Colleen,
I have received helpful comments since you tagged fellow members.
No, the bleeding hasn't stopped and I don''t know what to do about it. Had an MRI the other to address pelvic pain. Still waiting for the results. Otherwise I feel fine. Go figure.

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richardab | @richardab | Dec 6 7:11am

Sorry to hear that for you. Make sure your oncologist does more than just prescribe oral chemo, there are many more procedures which can be employed against this cancer.

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