Has anyone here had symptoms for years but no lesions? Last year I lost the use of my legs but went thru rehab and I am walking again. I still have many issues, extreme fatigue, dizziness, blurred vision, stability, headaches that I never used to get before, pins and needles, numbness, and spasms and urinary incontinence to name a few and I'm 46. All of my MRIs keep coming back normal. I know this is not in my head. My mother had MS and so I'm extremely familiar with the symptoms and everything I've been experiencing the last 2 years is deja vu of my mother's condition. Before 2 years ago, I was extremely active, running, social, and had a life. Now my life is just trying to survive through the day at work to pay bills. How long did you have symptoms before lesions appeared? Doctors have given me a diagnosis of Central Sensitization and Fibromyalgia which I'm not convinced of as all of my symptoms point to MS but lack the lesions. *sigh*