My Lp(a) was 312 nmol, had a NSTEMI 5 years ago at 57, and still have chronic angina. When I was prescribed Repatha it decreased to 267 nmol. 3 years ago I joined the Horizon study - a clinic trial for Pelacarsen. Pelacarsen lowers Lp(a) 80%. We think I am on the real deal, but I have not had Lp(a) tested since. There are at least 2 more studies on medications to lower Lp(a)…I would try to get into one if you can. Mayo Clinic should be able to advise you…

Otherwise, try to get on Repatha or Leqvio. They are PCSK9 inhibitors, but also helps us with high Lp(a). To give you a little peace, my mother’s Lp(a) was tested to be 267 nmol at 85 years old. She has never taken statins or other cholesterol lowering medications, but she did have a CABG at 73 and now experiencing mini strokes. My conclusion after a few years of worry but seeing her experience, is that high Lp(a) is not a death sentence, but we need to take extra good care of ourselves.

So be proactive and be good to yourself. I eat a modified Mediterranean diet and doing well now.

Hug cyber hugs…I know exactly how you feel.

Thea