"new" radiation therapy technique (SMART)

Posted by steveron @steveron, May 15 6:04pm

Stereotactic MR-guided on-table adaptive radiation therapy (SMART) for borderline resectable and locally advanced pancreatic cancer

Anyone experienced and/or familiar with this "new" radiation technique wherein the beam continually realigns in real time during treatment by tracking the tumor as the body vibrates/moves, which I believe is unlike "traditional" therapy wherein the beam is focused on one spot based on the previous day's scan?

Interested in more discussions like this? Go to the Pancreatic Cancer Support Group.

@rjm1942

Wondering if you have had this type of radiation. (MRI GUIDED) SMART. My husband is being scheduled for it and is quite worried about being able to tolerate it and what after treatment is like.

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I had this type of radiation for a tumor in what is left of my pancreas. I tolerated the procedure well. The radiation treatment occurred at KU.

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@ronninemire

I had this type of radiation for a tumor in what is left of my pancreas. I tolerated the procedure well. The radiation treatment occurred at KU.

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Did the treatment get rid of the tumor?

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I received Proton Beam Therapy at Mayo Clinic Rochester. I had zero side effects during treatment and the tumor responded very well. I believe they offer PBT in Minnesota and Arizona and are building one in Jacksonville.
https://www.mayoclinic.org/departments-centers/proton-beam-therapy-program/home/orc-20185488

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@stageivsurvivor

I believe this is the MRIdian system by the company ViewRay which was on the verge or had filed for bankruptcy protection and was searching for a buyer. There is or was a phase II trial of the technology at several sites in the US and one international site. The last update regarding the study was posted in 2022.
https://clinicaltrials.gov/study/NCT03621644

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This is interesting but very bizarre to me as my oncology care is under UCLA right now and one of the study locations cited is at UCLA. After reading about other posts about radiation treatments using Viewray I asked my UCLA medical oncologist about radiation he replied, “We don’t do that” and that they considered it basically dated technology. I can only assume now he’s not familiar with Viewray or MRIdean. After reading someone’s post a few months ago that Dr. Percy Lee (he’s at City of Hope in Irvine), had trained with the team at Harvard that did MRIdean radiation, I decided to set it up for myself. I hope to switch to City of Hope in Irvine for my pancreatic care once the construction on their hospital is completed (October 2025). Thank you @stageivsurvivor for posting the link to this study.

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@rjm1942

Wondering if you have had this type of radiation. (MRI GUIDED) SMART. My husband is being scheduled for it and is quite worried about being able to tolerate it and what after treatment is like.

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I had 3 sessions within a 2 week period on a liver lesion “remnant” of 0.9cm. I tolerated the procedure well and had little nausea and weakness, but i was also undergoing chemo at the same time period. Next week I meet with the radiologist/oncologist to find out how much of that lesion was obliterated.

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@mnewland99

Did the treatment get rid of the tumor?

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No, the tumor is not gone however, my CA 19–9 is 30, which is in the normal range. I am hoping that it continues to be inactive and the doctors have been very encouraged by the results of my radiation and chemo.

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@ronninemire

No, the tumor is not gone however, my CA 19–9 is 30, which is in the normal range. I am hoping that it continues to be inactive and the doctors have been very encouraged by the results of my radiation and chemo.

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Ok that’s great! Are you still receiving chemo?

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@mnewland99

Ok that’s great! Are you still receiving chemo?

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No I finished chemo in June 2024.

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@ronninemire

No I finished chemo in June 2024.

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Is the tumor characterized as NED, No Evidence of Disease? Ask your oncologist about that, please.

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@mnewland99

Is the tumor characterized as NED, No Evidence of Disease? Ask your oncologist about that, please.

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I will do that. I have an appointment at the oncologist this coming Monday. Thank you for your advice.

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