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Kappa light chain is elevated: Anyone dealing with this?
Blood Cancers & Disorders | Last Active: Apr 23 10:22am | Replies (58)Comment receiving replies
Hi,
I have high Kappa 2.62 and high kappa/lambda ratio 1.94. My last blood work was 2 weeks ago, and now says I have IgM lambda protein present in serum, but does not say any levels or numbers by it. I went to Mayo in 2022 for cardiomyopathy. They did tests for cardiomyopathy and blood work that caught the high FLC. My Mayo Cardiologist did not think I have MM or amylodosis. I hope they are right. This is scary stuff. So far in my home town they are watching it, and I have blood draws every 6 months.
I hope you continue to get answers you need. It helps to know there are others out there with same findings. Best regards.
Replies to "Hi, I have high Kappa 2.62 and high kappa/lambda ratio 1.94. My last blood work was..."
Hi,
My numbers are higher than yours and they’re checking me every year. My Kappa is 3.39 & Ratio is now 2.19 — so both High with Negative ANA (Auto-immune) so something is going on. My LDH is normal, but my ALP is at the highest end of normal which usually means something is happening in the Liver or the Bones. I’ve asked for an ISOENZYME test to determine where the high ALP is coming from. All these tests were done 7/24, so new tests to recheck are coming up in 7/25. I was having a bunch of weird symptoms that have now gone away. In terms of heart issues, I had AFib, which is an inflammatory condition with cardiac surgery to stop it 4/24. I no longer go into AFib so far. I’m wondering if heart issues can cause FLCs to spike without it being MGUS/MM/AML. Both parents died of Ca. As such, I have switched to an ultra low inflammatory diet, hoping to stop whatever is developing in its tracks.
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I’m no doctor but your numbers are similar to mine and I was diagnosed with MGUS. I have bloodwork done again in 3 weeks and am having a lot of anxiety