I have been getting infusions every 4 weeks for less than a year. This treatment for me has been life changing. Luckily I don’t have any side effects. MOST important is keeping yourself hydrated. I have been charting how I feel during the 4 week interval and noticed that an increase of symptoms return at the 3 week mark. I am wondering if I should get the infusions every 3 weeks. My pain and mobility are improving steadily.