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High insulin (not sugar) a cause of my neuropathy?

Neuropathy | Last Active: Nov 27 6:51am | Replies (6)

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@johnbishop

Hi @rickhood, I've always been in the pre-diabetic category and not wanting to make my neuropathy worse. I have idiopathic small fiber PN not related to diabetes but since learning about the metabolic syndrome a few years ago I started paying attention and focused on losing weight. There is another discussion on the "fix" that might be helpful:

-- Low-carb healthy fat living. Intermittent fasting. What’s your why?
https://connect.mayoclinic.org/discussion/low-carb-healthy-fat-living-intermittent-fasting-whats-your-why/
Here are some references that I found informative and useful:
-- The Metabolic Syndrome and Neuropathy: Therapeutic Challenges and Opportunities: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881591/
-- Metabolic syndrome as a risk factor for neurological disorders
https://pubmed.ncbi.nlm.nih.gov/21997383/
-- Dr. Jay Wortman - 'Undoing Atkins: A Cautionary Tale': https://www.youtube.com/watch?v=jIegMp5cWBY
-- Dr Jay Wortman Diabetes Remission is Surprisingly Simple!: https://www.youtube.com/watch?v=Cx6xw3wOAMc

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Replies to "Hi @rickhood, I've always been in the pre-diabetic category and not wanting to make my neuropathy..."

Thank you! That paper on Metabolic Syndrome was particularly interesting.

“Up until this last decade, it was generally believed that the underlying cause of neuropathy was hyperglycemia, irrespective of the type of diabetes (1 or 2). The more plausible and current hypothesis is that the MetS (metabolic syndrome) underlies the onset and progression of neuropathy and that obesity and its consequences are the driving factors leading to nerve injury.”

My BMI is 26.6 and need to get it down to 24-25. Fasting (no eating after 3-4pm) has worked great for me in the past, need to do that again.

Not clear if carb control helps or not, but that rather, weight loss, exercise, etc, is key. I should probably do both.

Once again, John may I say that you are a wealth of information. I have a lot of reading to do here. Thank you so much for your contributions. I hope it gives you comfort in knowing that you are helping and maybe the increased endorphins somehow give you a measure of relief.