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Transdermal HRT

Osteoporosis & Bone Health | Last Active: 5 hours ago | Replies (127)

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@hopefullibrarian

Hi newenglandtransplant, I hope your Evenity treatment is going well and you're adapting well to the HRT. I've had baseline bone markers, and then every three months during the Evenity treatment. I'll put all of the test results here for comparison:

P1NP/CTx 11/115 (Jan 2024) 102/355 (Apr 2024) 119/531 (Jul 2024) 92/496 (Oct 2024)

A lot has happened since the last time I posted anything about my treatment and progress, so, while I'm at it, I'll bring things up-to-date.

On October 31st I had my 10th and last Evenity injections. I'm stopping treatment because my insurance policy is changing on Dec 1 making the treatment unaffordable going forward.

Next week I'm changing the HRT treatment to an estradiol patch, and prometrium (oral micronized progesterone). I changed gynos to one willing to prescribe higher does of HRTs to prevent bone loss.

Also next week, I'll be getting a Reclast infusion, 2.5mg accompanied by intraveneous hydration.
In March, I'll test my BTMs again to determine when to move on to the next step which will be Alendronate.

Because my Evenity treatment is over, I got another DEXA and it included TBS.

Chronology of DEXAs and treatments:
Jan 2023 - First DEXA : Spine = -3.7 ; Left femoral hip = -3.2
May 2023 - Prolia injection
Jan 2024 - First Evenity injections
Mar 2024 - Started HRTs (low dose CombiPatch)
Apr 2024 - DEXA: Results N/A. Unfortunately, the radiologist made a mistake.
Oct 2024 - Last Evenity injections (10th treatment)
Nov 2024 - DEXA: Spine = -2.1 ; Left femoral neck = -2.6
Nov 2024 - TBS = 1.265
TBS reference range
> 1.3 = Normal
1.20-1.29 = Borderline bone quality
1.00-1.19 = Impaired bone quality
< 1.00 = Significantly impaired bone quality

I am over the moon with my results, and my specialists are blown away. It's the best results they've seen in such a short space of time.

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Replies to "Hi newenglandtransplant, I hope your Evenity treatment is going well and you're adapting well to the..."

Hi @hopefullibrarian , congratulations on your great results! If you don't mind, could you share the dose of estradiol that you used during evenity therapy, and the dose you are planning to increase to? Also, do you have tbs information from previous dxa scan report? If you have good article(s) re advantages in combination of a bisphosphonate and hrt, please share. Thanks a lot!

WOW! What spectacular results! You definitely weren't fooling around with this stuff. You did everything! Congratulations! You are an inspiration!