Hi Steve, it’s not surprising your mom’s red blood counts continue to drop if her bone marrow isn’t working correctly, not producing many new ones. MDS (Myelodyplastic syndroms) are a group of blood cancers that affect the bone marrow and can result in a low levels of blood cells. When MDS affects red blood cells it can lead to anemia and sometimes transfusion depenancy when counts get seriously low.
You mentioned your mom will be starting Azacitidine with Venetoclax. That combo has a good track record for helping people who are transfusion dependent and also slows blast production. Has she started her treatment cycle yet?