C. diff, SIBO and chronic nausea

Posted by jillannw @jillannw, Dec 25, 2018

I started 8 months ago with either food poisoning or a stomach flu. I have never recovered. I have had every test done and continue to suffer from nausea everyday. In the middle of this I was diagnosed with and treated for c-diff twice but because I didn’t have the classic symptoms the drs at Mayo thought they were false positives. I also was diagnosed and treated for SIBO twice. The nausea everyday which is where this all started never went away. Has anyone had this and come up with a solution?

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Profile picture for jananeedsmayo9 @jananeedsmayo9

When you say motion sickness issues, do you mean nausea? I have severe chronic nausea daily. Thank you for your help.

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Nausea, dizzy, hot flashes, cold sweet, exactly as when you’re pregnant or on a ship on a very rough sea

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Profile picture for cgper @cgper

Nausea, dizzy, hot flashes, cold sweet, exactly as when you’re pregnant or on a ship on a very rough sea

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Thank you 😊

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Profile picture for jananeedsmayo9 @jananeedsmayo9

Thank you so much for your help! Have you been to one of the Mayo Clinic’s, and did they help you?

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I haven’t.

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Profile picture for slkanowitz @slkanowitz

Many people experience nausea as a result of excess acid in the stomach. This occurs more when stomach is empty, particularly in the middle of night. It’s also seasonal, worse in spring and fall. The excess acid is likely to cause ulcers, and sometimes nausea is the main symptom without pain. Gallbladder disease causes nausea when stomach is full, after eating, especially after fatty food intake. The nausea from excess acid is temporarily relieved by creamy foods like ice cream, yogurt or milk, made worse by alcohol and spicy or acidic foods. Observing these associations can provide clues as to the cause. A test of antacids is helpful. If antacids relieve the nausea, then an H2 blocker like Pepcid (famotidine) and /or a PPI (protein pump inhibitor like omeprazole ) both OTC, can help if taken daily. Of course a discussion with your doctor about your observations and response to these meds is appropriate and so is asking for an endoscopy and gallbladder ultrasound. I hope you get some answers soon and relief!

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I never heard of excess acid in the stomach. Does it mean the stomach PH of a person with excess acid is lower than one with normal acid?

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Profile picture for mikeh0 @mikeh0

I never heard of excess acid in the stomach. Does it mean the stomach PH of a person with excess acid is lower than one with normal acid?

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Exactly. Stomach pH is even measured sometimes as part of diagnostic testing. That is not pleasant as a tube has to be put through the nose and into the stomach to do that. So a trial of ant acids, and or acid reducing medications is a reasonable and practical test to see if it helps the symptoms. persistent nausea however is something that should be addressed by a physician, preferably gastroenterologist. One must rule out serious causes of persistent nausea, such as stomach cancer, to be safe, which is done by endoscopy.

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Profile picture for slkanowitz @slkanowitz

Exactly. Stomach pH is even measured sometimes as part of diagnostic testing. That is not pleasant as a tube has to be put through the nose and into the stomach to do that. So a trial of ant acids, and or acid reducing medications is a reasonable and practical test to see if it helps the symptoms. persistent nausea however is something that should be addressed by a physician, preferably gastroenterologist. One must rule out serious causes of persistent nausea, such as stomach cancer, to be safe, which is done by endoscopy.

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What is the cause(s) of excess acidity in the stomach?
You would think this is supposed to reach a homeostatic and 'normal' acidity in a healthy individual that does not lead to any symptoms.
From what I understand you are saying the nausea can be caused by the ulcer/gastritis that is formed by the excess acid.
Do people have changes in acid levels over time , or temporarily during their life?
Another interesting question is does excess acidity in the stomach correlate with acid reflux? In other words, does it just swish around inside the stomach pack or does excess acidity also somehow precipitate the reflux reaction by some mechanism?

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Profile picture for mikeh0 @mikeh0

What is the cause(s) of excess acidity in the stomach?
You would think this is supposed to reach a homeostatic and 'normal' acidity in a healthy individual that does not lead to any symptoms.
From what I understand you are saying the nausea can be caused by the ulcer/gastritis that is formed by the excess acid.
Do people have changes in acid levels over time , or temporarily during their life?
Another interesting question is does excess acidity in the stomach correlate with acid reflux? In other words, does it just swish around inside the stomach pack or does excess acidity also somehow precipitate the reflux reaction by some mechanism?

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I'll keep it simple...mine is in waves. Low nausea, then night sweats, then daytime low nausea, then one bad day, then i feel great for about 3 weeks. Rinse and repeat.

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Profile picture for mikejjb123 @mikejjb123

I used to have a period when I would have nausea for several days or so if not weeks but it would go away for a time. Now I have low level nausea that remains constant and has not gone away for at least 2 months. Doesn't matter what I eat or don't. Raise my head when sleep or not. Any ideas what to do? Thanks.

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Yes the excess acid causes gastric inflammation and sometimes ulcers. You can google this to learn the physiology and pathophysiogy related. It tends to exacerbate and remit if one is prone to it. Many factors including genetics, diet, hormone secretion (like insulin triggered by food ingestion)), stress, meds, smoking, etc. affect the HCL production by tbe stomach’s parietal cells. There can be an excess or less often, a reduction in the ideal HCL production. Gastric acid pH can be tested during endoscopy. An interesting related read is Zollinger-Ellison Syndrome (rare). Enjoy delving into this!

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Profile picture for slkanowitz @slkanowitz

Yes the excess acid causes gastric inflammation and sometimes ulcers. You can google this to learn the physiology and pathophysiogy related. It tends to exacerbate and remit if one is prone to it. Many factors including genetics, diet, hormone secretion (like insulin triggered by food ingestion)), stress, meds, smoking, etc. affect the HCL production by tbe stomach’s parietal cells. There can be an excess or less often, a reduction in the ideal HCL production. Gastric acid pH can be tested during endoscopy. An interesting related read is Zollinger-Ellison Syndrome (rare). Enjoy delving into this!

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My mom’s nausea seems to correlate with her anxiety and depression. When they are treated, she does fine, but when she’s in a cycle, she complains of almost constant nausea.

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Profile picture for slkanowitz @slkanowitz

Yes the excess acid causes gastric inflammation and sometimes ulcers. You can google this to learn the physiology and pathophysiogy related. It tends to exacerbate and remit if one is prone to it. Many factors including genetics, diet, hormone secretion (like insulin triggered by food ingestion)), stress, meds, smoking, etc. affect the HCL production by tbe stomach’s parietal cells. There can be an excess or less often, a reduction in the ideal HCL production. Gastric acid pH can be tested during endoscopy. An interesting related read is Zollinger-Ellison Syndrome (rare). Enjoy delving into this!

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Some forums on Reddit seem to suggest that only 0.01% of gastritis is due to excess acidity. I can understand needing to reduce acid to heal an inflammation temporarily, but has it been shown that gastritis actually forms due to excess acidity, or is it rather exacerbated by even normal levels of acidity? I did find interesting the seasonal and hormonal variation, but I wonder if that is not accounted for by the body. In other words, would people have moderate symptoms that come on suddenly due to this natural variation, assuming it wasn't an acute injury like overdose of alcohol. I suppose aging and other factors could make us more sensitive to a process that was going on before.

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