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@murray3

I as well have mGus and also was told that an extremely small percentage of mGus actually transforms into Multiple Myeloma. I was diagnosed with mGus 20 years ago and was routinely and regularly being followed, tested, and monitored for that long-shot possibility of my mGus transitioning into Multiple Myeloma. However, at one of my regular routine 3-month check-ins with my oncologist on April 5, 2023, I was informed that my mGus had not transitioned into Multiple Myeloma but rather had transformed into an even rarer form of a Non-Hodgkin's Lymphoma similar to Waldenstrom's Macroglobulinemia. My paraproteins had transformed into the even rarer IgG-secreting lymphoplasmacytic lymphoma (LPL) I went through 5 cycles of chemotherapy (Bendamustine and Rituximab) before my 6th cycle was cancelled due to chemo causing very minimal desired results. Chemotherapy had in fact stagnated plateauing at levels considerably below what was anticipated. This led to my treatment changing November 2023 to a BTK Inhibitor called Zanubrutinib which I remain on and will do so for life or until it stops working. I take 4-80mg capsules of Zanubrutinib daily. If I were to miss or stop, all of my symptoms would return much stronger than before. My paraprotrin level, already relatively high, has stopped progressing thanks to Zanubrutinib; however, neither has my paraprotein level dropped or regressed either. Currently, my condition can best be classed as Stable.

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Replies to "I as well have mGus and also was told that an extremely small percentage of mGus..."

That’s great. Thanks for sharing.