What was your experience with bone marrow biopsy?

I'm happy for those who report little or no pain- times have changed it seems. I'm glad people are educated and have a choice of sedative or local pain treatments.
My BMB was 24 years ago and I still remember the incredible pain, deep and hurtful. I was I told I would be given something that would help with pain and also make me forget, clearly it didn't work. Back in those days I never asked the names of the medicines or had the internet for research. Believe me I have learned to my homework about doctors, diseases and treatment.
You could compare this pain to natural childbirth, which I had. I thought I was pretty tough. When you have a BMB and that horse syringe goes into the bone it was pretty close to the same intensity as natural childbirth, it just doesn't last as long.
On the bright side, even with a positive diagnosis of Chronic Lymphcytic Leukemia, CLL, how can I complain? After smoulding with this disease for 15 years with blood counts worsening, surprising my doctors and myself, without any treament I had a spontaneous regression and have had normal lymphocytes and blood counts for the last 10 years. I'm told there is no cure for CLL, even if it regresses a BMB could find it dormant in the marrow. Yet, I'll pass on that as long as my blood counts are normal.

gardening junkie- I bet they have for sure. For me, the instruments to get both samples look ancient. It is the skill of the PA i think that made mine less painful. Lidocane 1%. Your CLL is story is what many wish for. God's grace.
I hope it lays dormant for a long, long time.

I fully believe it is the skill and attention of the one doing the test. I had mine 60 years ago with only the local used at the time (they mentioned red soap). Of course I did not know in advance what was going to happen so apprehension did not play a role. Maybe they took more care since mine was done in a children's hospital. That was long before the assembly line approach to BMB. If I ever need a second one, I will make sure whoever does it meets the standard set 60 years ago.

Sorry, but I find it difficult to know how to enter the discussion without just replying to one post. Could the Coordinator tell us?
My question is: has anyone had significant improvement from DANAZOL tablets or a new injection I have been given:
REBLOZYL, for myelofibrosis? Thanks.

bmarkable. Your message will go to the end. Hopefully someone will give you an answer to that question.

As to the drug, I see Reblozyl is given to treat anemia in adults with certain blood disorders.
Summary. Danazol is a synthetic steroid and pituitary gonadotropin inhibitor used in the treatment of endometriosis and symptomatic treatment of severe pain and tenderness associated with benign fibrocystic breasts.

What are you being given the Danazol for?
From my experience and what i have read, I know some drugs are used for a number of conditions.

My experience was the best possible. I arrived, was put in a gown, and given a sedative. I woke up with a wad of gauze on my hip. I did not feel the procedure at all. When I got on my feet to go home, the only thing different was it felt like someone had knuckle punched me on my hip. It was felt for about four days.
Having been misdiagnosed originally, the bone marrow exam revealed an accurate diagnosis. Multiple tests were sent off but the diagnosis came from the pathologist’s microscopic analysis. The other tests were more for staging my myelofibrosis. Luckily for me, my only mutation was of JAK2 which was confirmed with the bone marrow.
Ask if you can have a sedative. If not, seek a place that does.

As long as I don't see the instruments in any procedure, I can go somewhere else in my head. That's also my approach to dental procedures. My BMB was done w Xanax and Lidocaine. Nothing terrible, all jabs felt momentary. Over in 10 minutes. But some people report bad pain. Everyo e is diff.

My BMB, was painless so I would not be concerned about getting a BMB.

Just have it done with sedation and U will do fine.

I have had 3 BMB in 6 months.
1. UCSF at my bedside/topical numbing agents. Only thing was pressure and the sound of the drill.
2. Done in a surgical center with sedation. Don’t recall much of anything.
3. Done at Stanford out patient clinic. Topical numbing agents like UCSF. Same result; pressure and drill sounds…No pain. Each had the same instructions; take it easy and do not shower for 24 hours.
All experiences were much better than I anticipated.