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Letrozole joints, bone loss, low platelets, high cholesterol

Breast Cancer | Last Active: Nov 1 6:54pm | Replies (35)
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@katrii

You and me both!! Letrozole was a No Go for me..lots of joint pain and mood swings.
Now on Anastrozole, and was put on a 600 mg, 3x/day Motrin regime for 5 weeks…but my thumb pain drove me to the Ortho Surgeon. Got shots in both thumbs, and he said I’m a good candidate for thumb joint replacement (9-12 mo recovery) and painful. I want to just STOP AI’s!!! Going to dr Friday to talk about it. I’m 71 almost…life’s too short for these mood swings and 24/7 joint pain!

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Replies to "You and me both!! Letrozole was a No Go for me..lots of joint pain and mood..."
flowergal | @flowergal | Oct 31 12:24pm

I have the constant lower back pain mentioned below too.
Anastrozole gave me a "trigger finger" something I knew nothing about before.
The combined impact on my body has been horrid.
In a few weeks I have an MRI and mammogram. I meet back with the surgeon. I've stopped the Letrozole. My oncologist says I have a 50% reoccurrence rate. (No oncotype done) So when I meet with the surgeon I'm going to discuss a double mastectomy.

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