Hello @hikerlou , I am not on this drug but I didn’t want to leave you unanswered. Living with advanced cancer is never ever easy, and I somewhat know what you are going through right now. Every relapse is a letdown and adds more fear and frustration.
I can’t tell you what you should do because only you know your situation health and quality of life. I can only tell you what I would consider in my situation. I would weigh how I feel now, with how I will feel if I don’t try it. I have had quite a few relatives on metformin, as diabetes runs in my family. It really isn’t bad, I just texted a friend and she said if that is the worst part she would go for it. She has been on it (metformin) for years with no problems.
My question would be is there a benefit to the current Mets, and can it help prevent new ones? How will my quality of life be, will I be able to do the things I love? I can try and then quit if it is awful and not helping, right?
All of that being said, I am heartbroken over every relapse of a breast cancer patient, regardless of stage. Did you decide to try Piqray? When do you expect your biopsies to be back?