← Return to Keytruda + Lenvima For Recurrent Endometrial Serrous Carcinoma

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@andreausa

I was diagnosed in Oct of 2023 with endometrial stage 2 high grade cancer. I had a total hysterectomy. I then did 6 months of Carbo/Taxol, my last treatment was April 2024. The chemo was knocing me out, so the doctors scheduled a CT for that week and results showed I was clear and could stop short of 6 rounds (I did 5 1/3 rounds total). Last blood test in May. In late June 2024 I started having non-specified abdominal pains - they kind of moved around (not a specific area). The pain worsened through July. I had a CT with contrast in August showing metastasis in my abdomen, like tiny grains of sand. Biopsy results were metastatic carcinoma, consistent with the type of endometrial cancer we thought was removed. Keytruda + Lenvima were the next options available to me. I started the immunotherapy 9/5/24, and have stayed on the 20mg Lenvima daily (I know - NO ONE has done this!) and I have good news to share. My CA 125 in August was 634, September 1,017, and now..... 131! I can't speak to anyone else's case, but it seems these medications were made for me. Side effects are minimal - tired, sore mouth, some hand sores that pop out of nowhere... but overall it's insanely encouraging. Fingers crossed, the future is looking brighter!!

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Replies to "I was diagnosed in Oct of 2023 with endometrial stage 2 high grade cancer. I had..."

That's really exciting news! I found the most recent study results of Keytruda + Lenvima here https://www.cancernetwork.com/view/lenvatinib-combo-yields-substantial-antitumor-activity-in-endometrial-cancer, for anyone else that's interested. It appears that 20mg daily is the prescribed treatment.