Everyone is different of course but I had a serious rebound effect after going off Prolia within 15 months, even w a biphosphonate directly following. Do plenty of research and maybe get a second and third opinion, you do not want to have happen to you what some of us are going through. It was never explained to me either the trauma of what the rebound could do to me. I am (was) and otherwise healthy, active, fit 67 yo
Who right now feels like a bent over old lady, trying desperately to get some vitality back. One of the main things I am working on is forgiving myself for not asking more questions and researching. But I am trying to look forward now, and just get better!