I have never heard of anyone using Trelstar. Are you in the United States? I was getting six-month Lupron shots and never really felt much of anything when they gave them to me.

When I was on Arbiterone for a couple of years. I asked my oncologist about reducing it to maybe help with the brain fog. She said fine. Go ahead and cut it down to three pills. My last PSA was .2 I switched to three pills 18 days before my next PSA test, PSA went up to 1 in 18 days. Not a very successful test though it did enable me to get a PSMA Pet test finally since my PSA went up so much. That’s the problem with BRCA2, it resents you trying to do anything to make you feel better.

By the way Trelstar is your ADT drug. Arbiterone is an anti androgen referred to as an ARSI not ADT.

Afters Zytiga stops working for you moving to Darolutamide is the preferred step. Lancet had an article about it, if you’re interested I could send you the link. Darolutamide has the least side effects of all the lutamide drugs.