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@gently I was not aware that the 2 year limit had been lifted on Tymlos. If so I would be happy. Can you share a link?
@kristie2, Prolia would have to be forever for @broken3 if she cannot tolerate bisphosphonates. (I am starting to believe I am in the same boat with bisphosphonates, which are needed after other meds at some point).
Replies to "@gently I was not aware that the 2 year limit had been lifted on Tymlos. If..."
@windyshores https://www.drugdiscoverytrends.com/fda-approves-removal-of-boxed-warning-from-label-for-osteoporosis-drug-tymlos/
The two year limit was placed on abloparatide because the rats developed osteosarcoma after 2 years of high dose PTH1-34 teriparatide.
It remains to understand and circumvent the mechanism of increase in osteoclastic activity that blunts bone acquisition in the later months of continuous PTH therapy.
I've now consulted with two physicians who are prescribing consecutive third year Tymlos. Some physicians are still operating from the black box, unaware of the lift.
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I have finished Evenity and just had my first injection of prolia. Since I did forteo, then 5 yr. if alendronate, I am thinking one year of prolia and the Evenity again then....who knows.
I am 76 now.