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Anyone Heard of Pirenzepine for Small Fiber Neuropathy?

Neuropathy | Last Active: 3 hours ago | Replies (108)
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@hjeff

has anyone used oral Pirenzepine pills for neuropathy? If so did it work and how much did you take?

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Replies to "has anyone used oral Pirenzepine pills for neuropathy? If so did it work and how much..."
jwneuropathy2021 | @jwneuropathy2021 | 3 hours ago

Hi,
I took half of a 25 mg pill. I got a bit lightheaded and then as the day went on my neuropathy got a lot worse body wide since I have small fiber and dysautonomia.

I haven't taken another one. I had to increase my pain meds. I am on day 2 and it is calming down but still worse. It obviously messes with something. I am trying to see if it would make one worse before getting better. There is some research that implies this.

I found one AI response that a trial somewhere had made a participant much worse with oral doses. It took a week to calm down.

Any insights? Thanks

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