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@tb39

I have been on Prolia for 8 years. I cannot handle the side effects any more so I told my doctor that I would not take another shot. I have had years of UTIs, severe muscle pain, unbearable cramps in my feet and ankles, sleep disturbances, bruising all over my legs, and frequent urination. Both my rheumatologist and my endocrinologist have suggested reclast or fosamax. The side effects of reclast terrify me. I would like to say no to both options but I am afraid of fracturing. My current T-score is as follows: Left hip -1.0, last year -1.3. Spine -0.4, last year -1.1. Right forearm -1.2, last year -0.3. I welcome any advice that you can give me. My next shot is due in December.

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Replies to "I have been on Prolia for 8 years. I cannot handle the side effects any more..."

If you have been on Prolia that long, my doctor would insist on Reclast @tb39. He would say Fosamax is not strong enough but if you cannot tolerate Reclast, that would be your only other option. Do you have any GERD/reflux?

To me, your DEXA scores are amazing. What were they when you fractured? I have read somewhere that even if your score does not plunge, your fracture risk could rise sharply. Talk to your doctor about this!

Keith McCormick wrote "Great Bones," a book that many of us use, and there is a section on how to carefully transition to Reclast from Prolia using bone markers.

Reclast will cause a few days up to a week+ of an acute phase reaction for many of us. For me fever of 99+, aches, headache but after the first one the second one tends not to have it, according to various articles. I did not have a fever the second time. Most people I know tolerate it pretty well. I have a few side effects that are tolerable, more tolerable than my fractures!