Currently the only thing that is helping my hives and skin rashes due to medication allergies are 20mg and sometimes more of prednisone daily. Unfortunately I have not found a replacement for the diuretic that I need to take for my heart failure. Tried many different diuretics and I am allergic to every one. I have tried the ice packs, steroid creams, OTC allergy relief ie: Allegra with only temporary relief. I am praying for a injectable diuretic in the near future. That would be the answer for me.