← Return to Does MGUS cause red blood cells (RBCs) to drop?

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@bojean

My Kappa light chain was 26.16 and ratio 1.58. I to have recheck of all the tests in 6 months. Got an appointment with my PCP and hope he will refer me to a new hematologist. Just trying to deal with the fatigue. This was diagnosed in June 2024. The oncologist I saw was contradictory, inappropriate, and dismissive. Thank you for your story. Trying to be thankful for the life I do have.

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Replies to "My Kappa light chain was 26.16 and ratio 1.58. I to have recheck of all the..."

MGUS is (supposed to be) asymptomatic. My kappa is about 300 and kappa/lambda is 29 (8 years). I now have some fatigue, but it is likely due to minor remaining long covid and new (urk) chronic kidney disease (I'm 70). It would be good to get complete bloodwork and any other tests to see why you have the fatigue. Granted, the stress of being diagnosed with MGUS can cause fatigue, but if this is ongoing then finding out why is important.

@bojean, the reason my MGUS was found was because my Hb was low. My PCP stated that MGUS can cause anemia. Just like what someone else in this thread said, the overproduction of the M-proteins crowds out production of other blood cells. My Hb flitters around the low end: sometimes normal, sometimes not. But I'm also in a wait and see pattern. I asked for 3 tests, 6 months apart (my dr wanted 2). Now I'm on an annual cycle.

I'm glad to hear you are getting a follow up test. I hope they are able to help you with your RBC.