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So other people with liver issues know an alternative
There is a hormone solution that you could try. They just finished a study that found that this hormone was as effective as ADT. Estradiol is the hormone. Well actually, that is the name of one patch. The hormone is estrogen. You wear a patch with the hormone in it. Your doctor could look up that study and find that it is just as effective as ADT. they had Richard Wassersug PHD do a one hour seminar on this. He has been using the patches for two years. He wrote the book “androgen deprivation therapy an essential guide for prostate cancer patients and their loved ones.” so this guy knows all about ADT.
If you have BRCA1 or BRCA2 you should not use this option.
Here is the webinar Wassersug gave at Ancan about estrogen/estradiol use instead of standard ADT
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That's interesting. Do you mean the PATCH trial?
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00100-8/abstract
I'm not sure it would make a difference for most of us (either way, participants still got gynomastia, hot flushes, etc and an elevated risk of heart disease), but as you mention, if taking estrogen instead of suppressing testosterone reduces the risk of liver damage, it could be useful for people showing concerning liver-related values in their bloodwork. Something else that it's worth keeping an eye on as this trial continues.
Key quote:
"Long-term data comparing tE2 patches with LHRHa show no evidence of a difference between treatments in cardiovascular mortality or morbidity. Oestrogens administered transdermally should be reconsidered for androgen suppression in the management of prostate cancer."