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Somebody tell me why CKD stage 3a or 3b is no big deal.
Kidney & Bladder | Last Active: Oct 11 3:55pm | Replies (40)Comment receiving replies
My gfr is 37 and doctor has suggested I take
Dapagliflozin
I am
Also on statin for high cholesterol and for the past month have been having muscle pain
Has anyone tried this drug for Chronic kidney failure ? It seems to have troubling side effects
Replies to "My gfr is 37 and doctor has suggested I take Dapagliflozin I am Also on statin..."
@looplu79
Dapagliflozin is Farxiga, which is advertised daily on the TV. When you say your doctor, are you talking of your endocrinologist, nephrologist, or PCP? There are different Farxiga doses for type 2 diabetes and CKD. Just because they advertise daily doesn't mean that it is an acceptable drug in both cases. If you go to their site and other medical websites, you will find that the adverse side effects can be harmful to some, and place you into later stages of CKD, which happened to me. However, some patients can benefit as well. In my opinion, the right approach is not the drug, but get further testing.
There are 2 eGFR common tests for kidney function, creatinine and Cystatin C. The latter in many cases is not covered by medical insurance, and can run a few hundred dollars or so. Neither of these 2 tests are definitive. The most accurate kidney function test is a 2.5 hour nuclear contrast study that will accurately define the function of each kidney and is called Iothalamate. If there is a discrepancy between the 2 common tests or depending upon the reliability of one over the other, this test is best served for those with Stage 3 or higher CKD including dialysis. Avoid getting possible severe side effects and higher CKD stages with Farxiga by going to your nephrologist and getting a more definitive nuclear kidney function study.
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@looplu79 I had a 36 and it went up to 41 with hydration, sometimes even higher. Did you hydrate well before your blood test?
Do you have type 2 diabetes?
I have been told that muscle loss affects the creatinine based eGFR so my doc also does a Cystain C GFR.
I looked up the drug:
Dapagliflozin is a medication used to control high blood sugar in people with type 2 diabetes123. It is a sodium-glucose cotransporter 2 (SGLT2) inhibitor that helps the kidneys remove sugar from the blood through urine, thereby decreasing blood sugar levels23. It can also lower the risk of heart attack, stroke, kidney disease, and hospitalization for heart failure in people with type 2 diabetes3.