I had an MRI guided biopsy and found it to be much better than the previous mammogram guided biopsy. Because the mammogram guided biopsy was quite awful, I asked my physician for a Valium to take before the procedure. Quite honestly, I believe the physician for the MRI biopsy was much more skilled than the one I had for the mammogram. I’m not sure how much the Valium helped, but this procedure was much less painful. They will place an IV for contrast. You will have a 5-10 minute time for them to find the area while lying on your stomach. You will feel the prick of the needle to deaden the area and then will only feel pressure once the biopsy is happening. It is a short procedure. You may have a bit of bruising in the area afterward. Best wishes to you.