I am taking Praluent, which is a drug in the same class. I was given an either or option - either Praluent or Repatha - insurance company approved Praluent first so that is what I went on. I have been on it now 10 months and the decrease in my bad cholesterol is totally amazing. Last cholesteral test was perfect - couldn't ask for more. I am sure Repatha would have done the same. I know others who are taking Repatha with good results.