What's your experience with duloxetine (US Brand Name; Cymbalta)?

Posted by d13 @d13, Jan 11, 2022

I was prescribed by my oncologist for the neuropathy in feet and hands. The chemotherapy treatments did this. This drug also states that it is used to treat depression and anxiety. As with any prescription medication, there could be side effects. And a huge list of what not to take with this drug. He also prescribed hydrocodone 5 mg, but to take half of pill four times daily for cancer pain. We’ll, when I got home and read about the Duloxetine use; one of the medications on the list was hydrocodone. I’m now waiting for a call from the oncologist office to see if I can take the Duloxetine with the hydrocodone. Can anyone at least tell me if they have ever taken this medication; Duloxetine? And any side effects?

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@journey2013

I have been taking Cymbalta 60 mg for years also for depression and haven't had any side effects. I noticed the Cymbalta by itself wasn't helping 100% anymore. Dr. put me on Wellbuttrin and dropped Cymbalta to 30 mg. That didn't help either so dropped Wellbuttrin and back to 60 mg Cymbalta. Will be seeing him next week and wondering if anyone else has needed to add another depression drug to Cymbalta and what their experience was?

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Just started Cymbalta last night. Bad cramps and diarrhea. Will these stay or go away?

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I switched from Wellbutrin to 60mg Duloxetine approximately 2 years ago for severe depression. I was concerned with weight gain and different side effects.
To date no significant side effects. No weight gain.
Sometimes I wonder if it’s effective, but overall I’m stable at least.

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These days if you have questions about drug interactions you can do a "GOOGLE" search for for example Cymbalta plus/+ Hydrocodone and you should get some useful info. Talk to your pharmacist if you need more clarification. I was prescribed Baclofen when I was taking Lyrica and Tramadol and the pharmacist didn't flag it. Turned out to be a no no.
When I was recovering from adrenal and renal surgery at Mayo recently I was told to stop taking the BP meds amlodipine and Losartan. I'm not sure if that order was compliments of the Mayo pharmacy or one of the Mayo physicians. I don't miss either one and I'm doing fine without them.

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