Pixiesusan, so good to hear back from you. My first bone biopsy in Oct. of 21 had me with CCUS. Almost a year later Sept. of 22 second bone marrow biopsy noted " The patients history of clonal hematopoiesis with TET 2 mutation is noted. Given the degree of thrombocytopenia and morphologic dysplasia, the current marrow is best classified as Myelodysplasia with Single Lineage Dysplasia. MDS-SLD" There is also the question could pathology got it wrong? I don't know? I have not had another biopsy since then. I had a Blood Flow Cytometry that showed "raised concern for myeloid neoplasm." Doctor explained to me that was MDS. All of this makes my head spin. Either way whatever it is low platelets are the problem and getting lower can cause spontaneous bleeding for both of us and the treatment would be the same. You are correct about the "low risk" pertains to our chances of getting AML. They haven't changed my risk factor even with them going lower. One book I read said " in the 20,000's/mm often indicates the MDS is evolving from lower-risk to higher risk." Others don't agree with that. I have read that people with higher risk (meaning all three cells involved) get down in the 20's and even lower and are not on treatment for the platelets. The book also stated that "low platelet count occurs least commonly as and initial sign of MDS." We are rare! I am 68 have some mobility issues that is why my doctor told me I cannot go lower than 30,000. She has a concern for me falling and causing a bleed. Like you my low platelets stated quite awhile ago in 2017. So I guess you could say we both are on quite a journey. I would love to talk to others with just platelets and see what their journey has been but seems to be so few of us. Hope you are feeling better and I look forward to following along with you on your journey if you post......take care.