@denisestlouie, I added your post to the Cancer: Managing Symptoms support group as well. I believe the changing of moods throughout the chemo cycle is familiar to patients, even if their pattern may differ from yours. For my dad's chemo, he was energetic and restless for the first few days (3-5) thanks to the steroids, next came the "nadir" or low point when many of his blood counts were low and energy was zapped. In the third week, mood and physical well being both started to equalize and normalize with the unfortunate tinge of regret that the cycle would soon be starting all over again.

It was helpful for the whole family to recognize the pattern. I'm glad that you've informed your sister. When she reminds me that the drugs are affecting your mood, are you able to believe her and take a break from the black cloud hanging (temporarily) over you? Do you mark your calendar to not make big decisions during that time?