PMR pain management with medical cannabis

I am down to Prednisone 4.5mg from 20 mg in January 2025. I have had 2 flares when I had to temporarily increase dosage.
I use THC/CBD/CBN 5mg (1:1) gummies for sleep. Which has allowed me to sleep a full 7-8 hours. I still wake up a little stiff but it is getting better. I am a nurse a worry about the slippery slope of cannabis but the benefit of sleep outweighs the low-dose of THC in the gummy.

i'd be very intersested in how you use it, thank you.

Another option for pain management might be Pain Reprocessing Therapy (PRT). See the group entries on Chronic Pain and search Pain Reprocessing Therapy.
Just having a mind-body tool to help with acute neuro-plastic pain has helped me tremendously. I don’t know if it will help with acute PMR or PMR flares because I haven’t had a flare since I have been practicing PRT.

Years back when suffering puke causing chronic lower back pain from 3 prior failed surgeries; I studied Cannabis versus Opioids at local Universities and a College online. I found that a majority of the weaker THC strains (mostly Sativa) included the highest percentages of CBD at that time, possibly different now due to all the Hybrid strains out there? Since my recent gift of PMR diagnosis, thought about it again, but have not. The THC, in conjunction with the proper Terpenes is what may help you with your pain, if you decide to visit a legal, licensed dispensary? CBD counteracts and will keep the Prednisone in your system longer, so I would stay away from that combo, if it were me. I would seriously suggest you study the Cannabis Terpenes and their function/purpose before you visit your dispensary and always follow the rule-"Go Slow-Start Low". Personally I am prescribed Tramadol for my pain, which works in small dose as the Opioid's do not and my refusal to take another drug thing that will hook me up for the remainder of life. I am sorry for your pain and discomfort from the PMR/Prednisone, but would ask you to really think about any outside source before making a decision on the Cannabis or not. Life has Side Effects-Dwell on the Positive
Due to the many side effects associated with prednisone, CBD may be a safer alternative.

CBD can inhibit the action of CYP3A4, a liver enzyme that metabolizes several kinds of drugs, including prednisone. Because of its inhibitory activity, it can cause the enzyme to slow down. This could cause the metabolism of prednisone to slow down as well, meaning prednisone would remain in the system for a longer time frame and more liable to cause more side effects.

I’m concerned that the Cannibis will interfere with my other meds. Do you have any info on that?

You can read the comments made by oldbtstlshrp2 yesterday.
There is a drug interaction checker on Drugs.com. I checked to see if there was an interaction between cannabis and Prednisone and there was no reaction reported.
We are all individual - what works for me may not work for you. I have chosen low dose THC CBD/CBN gummies for sleep only because I think sleep is critical. Once my sleep is fully established and waking up without pain I will cut the gummies in half and maybe even quarter. My objective is to get off all medications, especially Prednisone.
Pain reprocessing therapy helps with all of that.

I've read this on a few sites - "Hydrocortisone and prednisolone, commonly used CS, are both metabolized by the cytochrome P450 enzyme CYP3A65. CBD, as potent inhibitor of CYP3A when with these steroids may decrease glucocorticoid clearance and increase risk of systemic CS-induced side effects as well,"

I for the first time just tried those gummies …i was told to take one to see effects …it was amazing as I had 6 hours of uninterrupted sleep…will def . Use again

I am always reminded of the principle of n-of-one. What works for one person may or may not work for the other.
For now, THC/CBD/CBN gummy has helped me with sleep and middle of the night pain. That is, along with positive thoughts and beliefs that I got this!
My goal is to get off all meds, even the low-dose gummies. Movement always helps.
This is what I love about this opportunity to share ideas with others. Hope you find what works for you.

The Reaction is not from the THC, but the CBD content in Cannabis, different percentages by strains. For this reason there may be online; "No Reactions Shown". Any person wishing to use the Cannabis should observe the "Terpenes", their function for delivery of which compound and then take that into consideration for the Cannabis strain selected. Most people purchase Cannabis with the highest THC content, thinking it will work better and they get more relief-NOT TRUE! We have to be real careful when working with powerful side effects from Prednisone. CBD makes Prednisone Remain in our System Longer! UGLY.
If we come from a theoretical standpoint, there could potentially be drug interactions. Prednisone is a weak inducer, it is possible that it could change the breakdown or metabolism of CBD. It is something to be aware of.
CBD can inhibit the action of CYP3A4, a liver enzyme that metabolizes several kinds of drugs, including prednisone. Because of its inhibitory activity, it can cause the enzyme to slow down. This could cause the metabolism of prednisone to slow down as well, meaning prednisone would remain in the system for a longer time frame and more liable to cause more side effects.