I've also been dealing with multifocal LC since 2018. I've had five nodules radiated since then, and was informed by my radiologist during my last treatment (in June) that she wasn't willing to treat me with more. So far I've been fortunate not to have experienced any side effects. I have many more nodules that we're watching right now, and my oncologist is looking at Keytruda to possibly treat them. There's been an ongoing clinical trial at MD Anderson in Houston treating nodules with Keytruda. I was able to speak to the doctor in charge and he told me they're seeing success with the immunotherapy drug. The trial will continue until 2025, so he wasn't able to give me any numbers re: success rates, however. My oncologist continues to be hesitant to start it, he's always telling me how serious the possible side effects could be, but I'm running out of options at this point. I know it's only a matter of time before another lung nodule becomes malignant again.