Can one stop taking prolia after the first shot?

Posted by imatine @imatine, Mar 6, 2021

Hello everyone, my mom is 84 year old and she got osteoporosis since 8 years. She took prolia last October. She started to feel a lot of pain in her legs now. I am thinking she shouldn't take the 2nd shot but I am afraid of the consequences. Did anyone here stop the prolia at an early stage!? If so what happened? Thank you

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looplu79 | @looplu79 | Sep 23 9:48am

In reply to @janashelby "You have to go to a relay drug or risk vetebral fractures" + (show)

I stopped Prolia for about 6 months when I moved abroad
The result was active osteoporosis and fractured vertebrae
I am
Now back on it but thanks for advice about oral drug

Chris Trout, Volunteer Mentor | @artscaping | Sep 24 9:41pm

I stopped when my teeth started hurting after my first acceptance of Prolia!

Chris Trout, Volunteer Mentor | @artscaping | Sep 24 9:45pm

In reply to @artscaping "I stopped when my teeth started hurting after my first acceptance of Prolia!" + (show)

My Endocrinologist had me begin again with Fosamax on the first day of every week. I have had no negative symptoms.

maureenanne | @maureenanne | Sep 26 9:08am

In reply to @lissee "How are you doing today? Did you ever have any rebound fractures later? I had one..." + (show)

Hi lessee, thank you for reaching out. I am doing well, although I have had some bilateral sacral fractures, which showed on MRI on 7/30/24. I really don't think it had anything to do with rebound from prolia...it would have happened a lot sooner. I haven't tried anything else. It seems I'm becoming allergic to just about everything in my old age. I'm due for dexa at end of November, so I'll know then, but don't have great expectations. I hope you find a better solution for yourself...be well!

winkiev | @winkiev | Oct 4 11:30pm

You can find numerous anecdotal experiences of people who stopped Prolia after one shot. Here's mine - I had one shot of Prolia in February 2023; didn't take any follow-up medication and haven't had any fractures. But with anecdotal information you are not accounting for differences in age (I'm 68), fracture history (so far none luckily), diet and exercise, test results, etc.

Would be best to get advice from a qualified endocrinologist who is familiar with your mother's history. You could also ask this question on Dr. Lani Simpson's facebook page: https://www.facebook.com/doctorlani/. She wrote 'No-Nonsense Bone Health Guide'.

humphreysbr | @humphreysbr | Oct 5 12:49pm

From everything i have read, stopping Prolia you must take something else or you will lose more than when you started. I listened to Dr. Susan Otten's 10 things your doctor needs to know about osteoporosis which is on Utube. She explained that Prolia doesn't kill osteoclasts but basically separates them into one cell nucleus called osteomorphs which just wait for the drug to stop and they quickly form back into osteoclasts and resorb bone at a very rapid rate. So your mother would need to start on something else right away. Lots of people get off Prolia and take Fosomax while they decide if there is another drug to try. But waiting isn't a good idea.