There is a very informative discussion on the side effects of AREDS2 on this site. I recommend reading all of the posts.
https://connect.mayoclinic.org/discussion/areds/
I don’t remember if anyone else has mentioned rising blood pressure, but several people have had other side effects, including stomach upset/digestive track issues.

That is the issue I personally had. It was horrible and scary. I thought there was something seriously wrong with me. But the day I stopped taking the Preservision AREDS, the symptoms stopped.