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Support For Those Quitting Prolia

Osteoporosis & Bone Health | Last Active: 20 hours ago | Replies (152)

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@mayblin

@formisc You provided a fine example of careful planning and usage of bone markers for monitoring progress. Curiously, is your planned reducing dose to once every 2 weeks for 6 mo then once monthly thereafter for the second year a well studied regimen? Generic fosamax -alendronate comes in with many dose strength as you probably know. They could provide a way for titrating dose downward in a gradual manner.

Thank you for sharing your ongoing prolia cessation experience. Best wishes.

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Replies to "@formisc You provided a fine example of careful planning and usage of bone markers for monitoring..."

Thanks, mayblin.
No, I am doing this all on my own without any advice and knowledge other than what I have researched/read. Most studies recommend a follow-on period of between 1 to 2 years after Prolia although I recall I saw one article that mentioned a minimum of just 6 months but I can't find it again. With my low CTX scores, I could conceivably stop my Alendronate after 1 year but I prefer to be more conservative and ease off more gradually to reduce any shock to the system. I did come across several studies that mentioned that a half dose or fortnightly dose was effective in suppressing bone resorption but none referencing such use in withdrawal from Prolia. As for smaller dosages of Alendronate, I understand that these are only available for the brand-name Fosamax pills but I have not been able to find them in any pharmacy (and they would likely need a separate prescription) hence I have to go the fortnightly/monthly route