1. < Blood Cancers & Disorders

How high has anyone seen Lambda free light chain go with Mgus?

Posted by sammiemuss @sammiemuss, Aug 27 2:11pm

Going in Sept 3 for Bone marrow test .. symptom free but with accidentally finding of
Lambda free light chain serum test 1200.6 with Kappa 23.7 with ratio 0.02.. Mspike showed in 1 test out of 2.Pet scan with small nodule on lower lung with 5.1 uptake.
Plan 3 months lung CT.
Could this still be MGUS? Thx

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singularity | @singularity | Aug 27 3:19pm

It could be many things including a mistake at 1200.6.

I believe everyone needs both the medic team and to look after themselves but this is one area where you should rely on your medical team,- which also means you can still be an open minded skeptic.

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1 reply
sammiemuss | @sammiemuss | Aug 27 3:56pm
In reply to @singularity "It could be many things including a mistake at 1200.6. I believe everyone needs both the..." + (show)
@singularity

It could be many things including a mistake at 1200.6.

I believe everyone needs both the medic team and to look after themselves but this is one area where you should rely on your medical team,- which also means you can still be an open minded skeptic.

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Thank you , my thoughts have been to repeat test.

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Mentor
Patty, Volunteer Mentor | @pmm | Aug 28 7:29am
In reply to @sammiemuss "Thank you , my thoughts have been to repeat test." + (show)
@sammiemuss

Thank you , my thoughts have been to repeat test.

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@sammiemuss
I echo the counsel of @singularity. I also want to encourage you to call your hematologist or schedule a telehealth appointment at least to speak with him or her about the lab results.
My chart is innovative, and in many ways, a spectacular resource for patients, but on the downside… To receive lab results that are outside the normal range with no explanation is so anxiety provoking! I hope you can get some explanation soon. In the meantime, try to keep your anxiety at bay.
Hugs!

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1 reply
sammiemuss | @sammiemuss | Aug 28 8:55pm
In reply to @pmm "@sammiemuss I echo the counsel of @singularity. I also want to encourage you to call your..." + (show)
@pmm

@sammiemuss
I echo the counsel of @singularity. I also want to encourage you to call your hematologist or schedule a telehealth appointment at least to speak with him or her about the lab results.
My chart is innovative, and in many ways, a spectacular resource for patients, but on the downside… To receive lab results that are outside the normal range with no explanation is so anxiety provoking! I hope you can get some explanation soon. In the meantime, try to keep your anxiety at bay.
Hugs!

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Patty,
Yes I wished I would had ask more question , I even had a list but he noted would need to get bone marrow test.
I’m feeling good except positive for Covid now. Not sure if they will put off bone marrow test… thx for the hug I needed it today💐

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Mentor
Patty, Volunteer Mentor | @pmm | Aug 28 9:34pm

I’m so sorry you have Covid. There is still time to ask all your questions. Just feel better.
Patty

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slkanowitz | @slkanowitz | Aug 29 3:00am

Many Drs will repeat a lab test that comes back abnormal just to be sure. You mentioned an M spike in one of 2 tests, but were the light chains repeated? That may be prudent, and I would ask your doctor about it.

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1 reply
sammiemuss | @sammiemuss | Aug 31 5:15pm
In reply to @slkanowitz "Many Drs will repeat a lab test that comes back abnormal just to be sure. You..." + (show)
@slkanowitz

Many Drs will repeat a lab test that comes back abnormal just to be sure. You mentioned an M spike in one of 2 tests, but were the light chains repeated? That may be prudent, and I would ask your doctor about it.

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In the first test only the immunoglobulins were checked and it showed MSpike noted in lambda free light chain but no values was given.. That Doctor then sent me to an Oncologist /Hem who ordered a more complete test.. but that’s where it said MSpike not observed.. I don’t know if that meant to wasn’t there or they just didn’t observe it?
I’m feeling better now post Covid and very anxious for Bone Biopsy.
Also I should note I had ITP has a child and had a Splenectomy maybe it still related to Lambda now?
Thx for your input..

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slkanowitz | @slkanowitz | Sep 1 11:07am

I too have MGUS and have intermittent M spikes on labs. Mine is lambda FLC also. MGUS seems to occur more often in people with autoimmune conditions, like ITP and lupus, RA etc. I hope your BM bx is encouraging and all you need is monitoring. I have learned to put mine on the back burner mentally and I hope you can eventually as well.

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2 replies
sammiemuss | @sammiemuss | Sep 1 7:21pm
In reply to @slkanowitz "I too have MGUS and have intermittent M spikes on labs. Mine is lambda FLC also...." + (show)
@slkanowitz

I too have MGUS and have intermittent M spikes on labs. Mine is lambda FLC also. MGUS seems to occur more often in people with autoimmune conditions, like ITP and lupus, RA etc. I hope your BM bx is encouraging and all you need is monitoring. I have learned to put mine on the back burner mentally and I hope you can eventually as well.

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Thank you , I will post and update when I know …
I don’t have ITP now all blood work has been normal for years even platelets count , but thought I still may have light chains since 10 y/o .. and of course never checked .. maybe? Your note has helped my frame of mind today , thx again

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sallik74 | @sallik74 | Sep 2 11:26am
In reply to @slkanowitz "I too have MGUS and have intermittent M spikes on labs. Mine is lambda FLC also...." + (show)
@slkanowitz

I too have MGUS and have intermittent M spikes on labs. Mine is lambda FLC also. MGUS seems to occur more often in people with autoimmune conditions, like ITP and lupus, RA etc. I hope your BM bx is encouraging and all you need is monitoring. I have learned to put mine on the back burner mentally and I hope you can eventually as well.

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I have bone biopsy tomorrow
My free chains are 45.7 & kappa lambdo 9.14
M spike 5
What does this all mean?

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